Afflictions and illnesses

The following is a list of illnesses, diseases, sicknesses, afflictions, and other maladies shown in the series.

Cutie Pox
In The Cutie Pox, Twilight read this description from a book: "This puzzling pony plague afflicted a population of ponies back in the Paleopony period. Random cutie marks appeared all over the ponies' bodies, causing them to be forced to perform, without stopping, all the talents that came with them. The cause of the breakout was never discovered, and the cutie marks disappeared as mysteriously as they arrived." The only case seen in the series is contracted by Apple Bloom after an overdose of Heart's Desire plant petals. It is cured by the Seeds of Truth supplied by Zecora, which sprout only in the presence of a truthful confession.

Feather Flu
A number of ponies contract Feather Flu in Hurricane Fluttershy. Initially Rainbow Dash accuses Thunderlane of trying to get of out of setting a new tornado speed record with all the other Pegasus ponies when she hears him cough, although the cough actually came from the pony behind him, Blossomforth. Later at least seven other Pegasi are reported to have contracted Feather Flu, at least one (Thunderlane) requiring a hospital stay. A cure is not mentioned, though Twilight's disinfectant spray does not seem to prevent Thunderlane from catching the Feather Flu.

Food Poisioning
Food poisoning is seen in Applebuck Season when Pinkie Pie accidentally serves "Baked Bads" after Applejack's sleep-deprived attempts to help with muffin baking go awry. Nurse Redheart tends to a number of ponies who are seen squirming and writhing on their beds, many of them green-faced; some of them vomit. Apple Bloom takes on the same green-faced appearance in Family Appreciation Day while faking sickness, though Granny Smith sees through the ruse.

Pony Pox
Fluttershy pretends to be afflicted with Pony Pox in Hurricane Fluttershy in an attempt to avoid Rainbow Dash's recruitment efforts toward setting a new tornado speed record. Pony Pox may or may not be a real affliction; Fluttershy's faked symptoms include sneezing and being covered in red spots. Rainbow Dash "cures" Fluttershy by dousing her with water, causing the fake red spots to wash off.